| Beam Neutron Optimization for Boron Neutron Capture Therapy (BNCT) facility |
| Paper ID : 1057-ISCH |
| Authors |
|
lekkaa salah eldeen ramadan *1, Randa Mahmoud Mohamed2, Mona Mustafa Ahmed3, Rizk Abdelmonem Rizk4, Mostafa Azez Abdelwahab5 1department of physics , High institute for engineering of 15 May 2Ass.Prof of Radiation physics , Nuclear and Radiological Safety Research Center, Egyptian Atomic Energy Authority 3Ass .prof of nuclear physics , department of physics, faculty of science , Helwan university 4prof of nuclear physics in department of physics , faculty of science , Helwan university . 5prof of nuclear engineering, Nuclear and Radiological Safety Research Center, Egyptian Atomic Energy Authority |
| Abstract |
| This work aims to focus on beam shaping assembly (BSA)’s design and optimization for boron neutron capture therapy (BNCT) facility based on a proton accelerator. The BSA optimization is simulated by MCNP Monte Carlo code. The output neutron beam characteristics are compared to that recommended by the international atomic energy agency (IAEA). The dose components that contributed to the absorbed dose are simulated using MCNP code based on the neutron interactions mode and boron concentration values taking into account the relative biological effectiveness (RBE) factors. The total effective dose in brain tumor and healthy tissues for different values of 10B concentration are compered to calculate the therapeutic gain (TG). The results indicated that the healthy tissues at the skin surface, skull and beyond the tumor receive the lowest radiation dose. TG may be used as a fast evaluation of the impact of varying 10B concentrations on the therapeutic outcome, and treatment optimization. |
| Keywords |
| BNCT facility, MCNPX computer code, Monte Carlo method |
| Status: Abstract Accepted (Poster Presentation) |