Ulcerative colitis mediology and causes
Paper ID : 1086-ISCH
Authors
Asmaa Abdelsalam Emary *1, Ahemed Said Alazzouni2, Basma Nasr Hassan2, Neiven Mahran Ahmed3, Mohammed Hassany Gad4
1Teaching assistant in zoology Entomology department faculty of science Helwan university cairo
2Department of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt.
3Department of medical science, Faculty of Dentistry , Sinai university , Ismailia
4Department of histology, Faculty of Dentistry , Sinai university , Ismailia
Abstract
Ulcerative colitis (UC) is an immune-mediated
chronic inflammatory bowel disease (IBD) characterized by relapsing and remitting mucosal
inflammation in the colon.
The worldwide prevalence of UC is on the rise and patients often experience debilitating symptoms
including diarrhea, abdominal pain, rectal bleeding, extra-intestinal manifestations, and an increased risk of colorectal cancer.
Ulcerative colitis always involves the rectum and extends proximally in a continuous fashion to involve part or the entire colon that can be
diffusely ulcerated. Skip lesions are not seen (although focal appendiceal or cecal inflammation
occasionally may be present in those with left sided disease). Disease of the entire colon is
termed pancolitis. Disease limited to the rectum or rectosigmoid may be referred to descriptively
as ulcerative proctitis or ulcerative
proctosigmoiditis. The small intestine is normal, although mild mucosal inflammation of the distal
ileum, backwash ileitis, may be present in severe cases of pancolitis (Kumar et al., 2018).
Keywords
Ulcerative colitis Inflammatory bowel disease Colon
Status: Abstract Accepted (Poster Presentation)